Takata Laboratory
Institute for Basic Science - Center for Genomic Integrity
Publications
2021-Present
Oh JM, Kang Y, Park J, Sung Y, Kim D, Seo Y, Lee EA, Ra JS, Amarsanaa E, Park YU, Lee SY, Hwang JM, Kim H, Schärer O, Cho SW, Lee C, Takata K, Lee JY, Myung K. MSH2-MSH3 promotes DNA end resection during homologous recombination and blocks polymerase theta-mediated end-joining through interaction with SMARCAD1 and EXO1. NAR, 6/2023. PMID: 37140056
Yi G, Sung Y, Kim C, Ra JS, Hirakawa H, Kato TA, Fujimori A, Kim H, and Takata K. DNA polymerase θ-mediated repair of high LET radiation-induced complex DNA double-strand breaks. NAR, 2/2023. PMID: 36805268
2016-2020
Hwang T, Reh S, Dunbayev Y, Zhong Y, Takata Y, Shen J, McBride KM, Murnane JP, Bhak J, Lee S, Wood RD, Takata KI. Defining the mutation signatures of DNA polymerase θ in cancer genomes. NAR Cancer, 9/2020. PMID: 32885167
Liu X, Jiang Y, Takata K, Nowak B, Liu C, Wood RD, Hittelman WN, Plunkett W. CNDAC-induced DNA double strand breaks cause aberrant mitosis prior to cell death. Mol Cancer Ther., 9/2019. PMID: 31501277
Tomida J, Takata K, Bhetawal S, Person MD, Chao HP, Tang DG, Wood RD. FAM35A associates with REV7 and modulates DNA damage responses of normal and BRCA1-defective cells. EMBO J., 6/2018;37(12). PMID: 29789392
Takata K, Reh S, Yousefzadeh MJ, Zelazowski MJ, Bhetawal S, Trono D, Lowery MG., Sandoval M, Takata Y, Lu Y, Lin K, Shen J, Kusewitt DF, McBride KM, Cole F, Wood RD. Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance. PLoS Genetics, 6/2017;13(6):e1006818
2011-2015
Takata K, Tomida J, Reh S, Swanhart LM, Takata M, Hukrieda NA, Wood RD. Conserved overlapping gene arrangement, restricted expression and biochemical activities of DNA polymerase ν (POLN). J Biol Chem., 8/2015. PMID: 26269593
Tomida J, Takata K, Lange SS, Schibler AC, Yousefzadeh MJ, Bhetawal S, Dent SY, Wood RD. REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ. Nucleic Acids Res. 1/2015. PMID: 25567983.
Yousefzadeh MJ, Wyatt DW, Takata K, Mu Y, Hensley SC, Tomida J, Bylund GO, Doublié S, Johansson E, Ramsden DA, McBride KM, Wood RD. Mechanism of suppression of chromosomal instability by DNA polymerase POLQ. PLoS Genetics, 10, e1004654, 10/2014. PMID: 25275444.
Takata K, Reh S, Tomida J, Person MD, Wood RD. Human DNA helicase HELQ participates in DNA interstrand crosslink tolerancewith ATR and RAD51 paralogs. Nature Communications, 2013;4:2338. PMID: 24005565.
Christov PP, Yamanaka K, Choi JY, Takata K, Wood RD, Guengerich FP, Lloyd RS, Rizzo CJ. Replication of the 2,6-Diamino-4-hydroxy-N(5)-(methyl)-formamidopyrimidine (MeFapy-dGuo) Adduct by Eukaryotic DNA Polymerases. Chem Res Toxicol., 25(8):1652-61, 8/2012. e-Pub 7/2012. PMID: 22721435.
Lange SS, Takata K, Wood RD. DNA polymerases and cancer. Nat Rev Cancer, 11(2):96-110, 2/2011. PMID: 21258395.
2006-2010
Takata K, Arana ME, Seki M, Kunkel TA, Wood RD. Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity. Nucleic Acids Res., 38(10):3233-3244, 6/2010. PMID: 20144948.
Yamanaka K, Minko IG, Takata K, Kolbanovskiy A, Kozekov ID, Wood RD, Rizzo CJ, Lloyd RS. Novel enzymatic function of DNA polymerase nu in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-links. Chem Res Toxicol., 23(3):689-695, 3/2010. PMID: 20102227.
Takata K, Wood RD. Bypass specialists operate together. EMBO J, 28(4):313-4, 2/2009. PMID: 19225445.
Nakamura R, Takeuchi R, Takata K, Shimanouchi K, Abe Y, Kanai Y, Ruike T, Ihara A and Sakaguchi K. TRF4 is involved in polyadenylation of snRNAs in Drosophila melanogaster. Mol Cell Biol, 28(21):6620-6631, 11/2008. PMID: 18765642.
Saitoh T, Kuramochi K, Imai T, Takata K, Takehara M, Kobayashi S, Sakaguchi K and Sugawara F. Pdodphyllotoxin directly binds a hinge domain in E2 of HPV and inhibits and E2/E7 interaction in vitro. Bioorg Med Chem, 16(10):5815-5825, 5/2008. PMID: 18396405.
Arana ME, Takata K, Garcia-Diaz M, Wood RD, Kunkel TA. A unique error signature for human DNA polymerase nu. DNA Repair (Amst), 6(2):213-23, 2/2007. PMCID: PMC1950682.
Kanai Y, Ishikawa G, Takeuchi R, Ruike T, Nakamura R, Ihara A, Ohashi T, Takata K, Kimura S and Sakaguchi K. DmGEN shows a flap endonuclease activity, cleaving the blocked-flap structure and model replication fork. FEBS J, 274(15):3914-3927, 8/2007.
Takata K, Shimizu T, Iwai S, Wood RD. Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol. J Biol Chem., 281(33):23445-55, 8/2006. e-Pub 6/2006. (Faculty of 1000 Highlight)
Shimanouchi K, Takata K, Yamaguchi M, Murakami S, Ishikawa G, Takeuchi R, Kanai Y, Ruike T, Nakamura R, Abe Y, Sakaguchi K. Drosophila damaged DNA binding protein 1 contributes to genome stability in somatic cells. J Biochem., 139(1):51-58, 1/2006.
Morimura T, Noda N, Kato Y, Watanabe T, Saitoh T, Yamazaki T, Takata K, Aoki S, Ohta K, Ohshige M, Sakaguchi K and Sugawara F. Identification of antibiotic clarithromycin binding peptide displayed by T7 phage particles. J Antibiot (Tokyo), 59(10):625-632, 10/2006.
Ruike T, Takeuchi R, Takata K, Oshige M, Kasai N, Shimanouchi K, Kanai Y, Nakamura R, Sugawara F and Sakaguchi K. Characterization of a second proliferating cell nuclear antigen (PCNA2) from Drosophila melanogaster. FEBS J., 273(22):5062-5073, 11/2006.
Murakami S, Kamisuke S, Takata K, Kasai N, Kimura S, Mizushina Y, Ohta K, Sugawara F and Sakaguchi K. Site directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8 kDa domain of DNA polymerase beta. Biochem Biophys Res Commun., 350(1):7-16, 11/2006.
2000-2005
Ishikawa G, Kanai Y, Takata K, Takeuchi R, Shimanouchi K, Ruike T, Furukawa T, Kimura S and Sakaguchi K. DmGEN, a novel RAD2 family endo-exonuclease from Drosophila melanogaster. Nucleic Acids Res., 32(21):6251-6259, 12/2004.
Takata K, Yoshida H, Yamaguchi M and Sakaguchi K. Drosophila damaged DNA-binding protein 1 is an essential factor for development. Genetics, 168(2):855-865, 10/2004.
Takata K, Shimanouchi K, Yamaguchi M, Murakami S, Ishikawa G, Takeuchi R, Kanai Y, Ruike T, Nakamura R, Abe Y and Sakaguchi K. Damaged DNA binding protein 1 in Drosophila defense reactions. Biochem Biophys Res Commun., 323(3):1024-1031, 10/2004.
Takeuchi R, Oshige M, Uchida M, Ishikawa G, Takata K, Shimanouchi K, Kanai Y, Ruike T, Morioka H and Sakaguchi K. Purification of Drosophila DNA polymerase zeta by REV1 protein-affinity chromatography. Biochem J., 382(Pt 2):535-543, 9/2004.
Takata K, Inoue YH, Hirose F, Murakami S, Shimanouchi K, Sakimoto I, Sakaguchi K. Spatio-temporal expression of Drosophila mitochondrial transcription factor A during development. Cell Biol Int., 27(4):361-374, 2003.
Ishibashi T, Kimura S, Yamamoto T, Furukawa T, Takata K, Uchiyama Y, Hashimoto J and Sakaguchi K. Rice UV-damaged DNA binding protein homologues are most abundant in proliferating tissues. Gene, 308:79-87, 4/2003.
Takata K, Ishikawa G, Hirose F, Sakaguchi K. Drosophila damage-specific DNA-binding protein 1 (D-DDB1) is controlled by the DRE/DREF system. Nucleic Acids Res., 30(17):3795-3808, 9/2002. PMCID: PMC137413.
Takata K, Yoshida H, Hirose F, Yamaguchi M, Kai M, Oshige M, Sakimoto I, Koiwai O, Sakaguchi K. Drosophila mitochondrial transcription factor A: characterization of its cDNA and expression pattern during development. Biochem Biophys Res Commun., 287(2):474-483, 9/2001.
Oshige M, Yoshida H, Hirose F, Takata K, Inoue Y, Aoyagi N, Yamaguchi M, Koiwai O, Matsukage A, Sakaguchi K. Molecular cloning and expression during development of the Drosophila gene for the catalytic subunit of DNA polymerase epsilon. Gene, 256(1-2):93-100, 10/2000.